Healthcare costs keep climbing, and yet patients and employers often feel powerless to change the system. What if outsiders—those not steeped in the traditions of healthcare—are actually the ones best positioned to fix it?

Hospitals are under immense pressure: burned-out clinicians, outdated systems, and rising costs have made delivering care harder than ever. 

One in four Americans is enrolled in Medicaid, yet the system designed to support them is constantly at risk—underfunded, politically vulnerable, and often overlooked.

Three simple questions plague every American seeking healthcare: Where should I go? When can I be seen? And how much will it cost me? Despite seeming basic, these questions have remained largely unanswerable—until now.

A new federal law is reshaping how healthcare is paid for and delivered in America.

Fresh off a $240 million fundraise from Oak HC/FT and A16Z, Ambience Healthcare is on a mission to kill medical billing — and build “Iron Man suits for doctors.”

Dexcom generates more than $4 billion in annual revenue and has a market cap north of $30 billion, making it one of the biggest digital health companies in the world. And it all started with a better way to measure blood sugar.

More than a thousand AI medical devices have FDA clearance, yet fewer than two percent of radiologists actually use them.

When Andrew Lacy launched Prenuvo, most of the medical establishment dismissed it as fringe. Now, some of those same skeptics are collaborating with him on research.

In their first podcast since going public, Omada Health CEO Sean Duffy joins us to reflect on the journey to bend the curve of chronic disease.

What does one do after selling their company to Amazon for $1 billion? Start a new one, of course.

Most medical care is backed by varying types of evidence—yet we apply higher standards to digital health tools before they’re trusted, adopted, or reimbursed.

Most AI in healthcare promises superintelligence—but what if that’s the wrong goal entirely?

Over half of Americans now live with at least one chronic condition, yet our healthcare system still revolves around episodic, reactionary care instead of continuous, coordinated support.

US healthcare has more unproductive labor and more unstructured data than any other industry, making it both especially vulnerable to disruption from generative AI and especially unprepared for it.

Over 160 million Americans are served by Optum, yet many still don’t fully understand what it actually does—or why it matters.

Women make 80% of healthcare decisions and outspend men two to one on care—yet when it comes to designing, funding, and scaling health tech, they’re still treated like a niche.

The average American family spends over $24,000 a year on healthcare, and costs continue to rise faster than inflation. Why can't we create a healthcare system that delivers more value for less money?

Each year, 2 million Americans are diagnosed with cancer and face a fragmented, overwhelming healthcare system with minimal guidance between doctor visits, even as they make life-altering decisions.

In this episode, we talk with Mario Schlosser, co-founder and CTO of Oscar Health, about building a tech-first health insurance company in an industry notorious for poor customer experiences.